The lymphoma is in only 1 lymph node area or lymphoid organ such as the tonsils (I). Refractory NHL means that the lymphoma has not responded to treatment.

The staging system used for Hodgkin lymphoma is the Lugano classification, which is based on the older Ann Arbor system. If it comes back in the same place that the lymphoma first started, it’s called local relapse. The cancer is showing diffuse or disseminated involvement of one or more extra-lymphatic organs with or without regional lymph node involvement. National Comprehensive Cancer Network, Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Hodgkin Lymphoma, Version I.2018 -- December 20, 2017. Hodgkin lymphoma is an uncommon cancer that develops in the lymphatic system, which is a network of vessels and glands spread throughout your body.

It may also affect other groups of lymph nodes on the same side of the diaphragm. Stage IV symptoms depend on the type and extent of the cancer.

It has 4 stages, labeled I, II, III, and IV. Imaging tests. Please note, our regular chat hours are Monday-Friday, 10AM to 7PM Eastern Time. This means that a low-grade (indolent) NHL usually relapses as a low-grade lymphoma. 2014;32:3059-3068.

See Treating B-cell Non-Hodgkin Lymphomas and Treating T-cell Non-Hodgkin Lymphomas for more on this. It's usually labeled by adding the letter X to the stage.

Chapter 103: Non-Hodgkin’s lymphoma. Practice Guidelines in Oncology: B-cell Lymphomas. The lymphoma has also spread into tissue near the lymph nodes. Recurrence may occur at any time, including shortly after the first treatment or years later.

If you would rather reach us by phone, you can call the LLS IRC toll-free line at 1-800-955-4572 from 9am-9pm ET Monday-Friday or send us a message at https://www.lls.org/content/contact-us?UID=LLS-26-756.

We would really like to chat with you, so please try contacting us again later. In: DeVita VT, Lawrence TS, Rosenberg SA, eds. This could be, for example: It could also indicate the cancer has affected a single extra-lymphatic site without involving any lymph nodes.

DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology. Animals | Cancer | Causes | Chemotherapy | Clinical Trials | Diffuse | Follicular | GVHD | Hair Loss | Immunotherapy | Leukemia | Lymphoma | MALT | Mantle Cell | Monoclonal Antibodies | Nutrition | Prevention | Prognosis | Radiotherapy | Remission | Research and Education | Share Your Story | Side Effects | Testing | Blogs | Videos. Philadelphia, Pa: Lippincott Williams & Wilkins; 2015.

8th ed. Often the stages 1 to 4 are written as the Roman numerals I, II, III and IV. Hodgkin’s lymphoma is treatable, especially in its early stages.

You doctor or specialist nurse can explain what stage you have and what this means in your situation. Together, we’re making a difference – and you can, too. National Cancer Institute. Freedman AS, Jacobson CA, Mauch P, Aster JC. 2. Some people with stage 2 bulky lymphoma might have advanced disease, depending on their circumstances.

Aggressive Non-Hodgkin’s Lymphomas (NHLs) are fast growing cancers (as opposed to indolent cancers). Lymphoma is in lymph nodes both above and below the diaphragm. For reprint requests, please see our Content Usage Policy. Lymphoma is called stage IIE if it’s in one organ and the nearby lymph nodes. The stage of lymphoma describes the extent of spread of the tumor using the Roman numerals I, II, III, or IV (1 through 4).

Whether you want to learn about treatment options, get advice on coping with side effects, or have questions about health insurance, we’re here to help. There are different staging systems for skin lymphoma and childhood NHL.

Roschewski MJ, Wilson WH. Volume 380, Issue 9844, Pages 848-57. Lymphedema and Lymphoma: What Are The Causes?

HL is found in 2 or more lymph node areas on the same side of (above or below) the diaphragm, which is the thin muscle beneath the lungs that separates the chest and abdomen (II).

What does it take to outsmart cancer? If it spreads, it's usually to another set of nearby lymph nodes. 2. Our team of expert journalists brings you all angles of the cancer story – from breaking news and survivor stories to in-depth insights into cutting-edge research.

The cancer has affected two or more lymph node regions, but both must be on the same side of the body's diaphragm. This means that you have lymphoma on both sides of the diaphragm. Benign cancers are the kind that don't spread and don't threaten one's life. But the cancer is still limited to a section of the body either above or below the diaphragm.

For example, this might include nodes in the underarm and neck area (II) but not the combination of underarm and groin nodes (III). In: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Accessed at https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf on May 2, 2018. This is often called the extent of lymphoma. In both of these systems there are 4 stages.

Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing. Another example (see below) is that the lymphoma is in lymph nodes above the diaphragm, as well as lymphoma in the spleen. Your treatment also depends on: You may have just one type of treatment, or a combination of treatments. Cancer.org is provided courtesy of the Leo and Gloria Rosen family. Making Strides Against Breast Cancer Walks, Common Questions About the COVID-19 Outbreak, Imaging tests, which typically include a chest x-ray, CT scan of the chest/abdomen/pelvis, and PET scan, Bone marrow aspiration and biopsy (sometimes, but not always done). Read our information about coronavirus and cancer.

Extranodal sites include the lungs, liver, blood, bone marrow, kidneys, brain and spinal cord. This term is often used to describe large tumors in the chest.

But sometimes a low-grade type of NHL relapses as a high-grade (aggressive) type of NHL. Stages of non-Hodgkin lymphoma. Tests used to gather information for staging can include: In general, the results of imaging tests such as PET or CT scans are the most important when determining the stage of the lymphoma. The American Cancer Society is a qualified 501(c)(3) tax-exempt organization. If you require more information or need assistance please contact us. Learn more about these partnerships and how you too can join us in our mission to save lives, celebrate lives, and lead the fight for a world without cancer. They also measure the size of the lymphoma.

This process is called staging.

A staging system is a way for the cancer care team to sum up the extent of a cancer’s spread. Knowing the stage helps your doctor to decide what treatment you need. In addition to the stage number, the letters A, B, E or S may be used to further classify the stage of HL. HL is found in lymph node areas on both sides of (above and below) the diaphragm (III).

In 2011, Leukemia & Lymphoma Society data revealed that there were roughly 159,846 people living with Hodgkin lymphoma or in remission and approximately 502,943 people with non-Hodgkin lymphoma.

Blood tests. Or write us. the nodes and organs of the lymphatic system – these are called lymphatic sites, areas outside of the lymphatic sites – called extranodal (or extralymphatic) sites, lymphoma in a single lymph node or one group of lymph nodes, or an organ of the lymphatic system (such as the thymus), your lymphoma is in two or more groups of lymph nodes, your lymphoma is in an extranodal site and one or more groups of lymph nodes (2E), your lymphoma is in an extranodal site and lymph nodes are affected, your lymphoma is in more than one extranodal site, for example the liver, bones or lungs, the type of lymphoma (the type of cells the cancer started in), the grade of cancer (the appearance of cells or the number of a certain cells in your lymphoma).

Lymphoma is in 2 or more groups of lymph nodes.


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