}, National Library of Medicine

It has been shown that the tumor population growth dynamics in a periodically varying environment can drastically differ from the one in a fixed environment. He is known primarily for his research on genome evolution, especially in microbes and viruses, host-parasite coevolution, and more specifically, functions and evolution of CRISPR-Cas systems. SM-Facebook All Rights Reserved. This latter outcome can be avoided by... A crucial factor in mitigating respiratory viral outbreaks is early determination of the duration of the incubation period and, accordingly, the required quarantine time for potentially exposed individuals.

Thus, the environment of a tumor can potentially be manipulated to suppress cancer progression. 8600 Rockville Pike Keywords: Bacilladnaviridae; CRESS DNA viruses; Circoviridae; Geminiviridae; Genomoviridae; International Committee on Taxonomy of Viruses (ICTV); Nanoviridae; Redondoviridae; Smacoviridae; virus classification; virus evolution. fill: none; Consent for publication. } fill: #FFFFFF;

Bethesda, MD 20894, Copyright Using integrated comparative genomics and machine learning techniques, we... No abstract available stroke: #FFFFFF;

Here, we analysed the RNA virome from approximately 10 l water from Yangshan Deep-Water Harbour near the Yangtze River estuary in China and identified more than 4,500 distinct RNA viruses, doubling the previously known set of viruses. stroke-miterlimit: 10; SM-Youtube fill: #FFFFFF; The modified bases play diverse biological roles that include both regulation of transcription and translation, and protection against restriction endonucleases and antibiotics. In fact, it has been suggested that plant NSR viruses may have originated from arthropod viruses that evolved to also infect plants (Whitfield et al., 2018; ... Studies on three severe class of coronaviruses have shown that hydrophobic interaction in receptor binding motif for SARS-COV and SARS-COV-2 could allow the spike protein for zoonotic transmission, ... Integrative analysis of SARS-CoV-2 should promote our understanding of the virus dynamics and interactions with hosts and environments. National Center for Biotechnology Information, Singapore University of Technology and Design, Mapping CRISPR spaceromes reveals vast host-specific viromes of prokaryotes, Machine-learning approach expands the repertoire of anti-CRISPR protein families, Doubling of the known set of RNA viruses by metagenomic analysis of an aquatic virome, Diverse enzymatic activities mediate antiviral immunity in prokaryotes, Deep Roots and Splendid Boughs of the Global Plant Virome, Modified base-binding EVE and DCD Domains Implicated in the Origins of Programmed Cell Death and the piRNA Pathway, Evolutionary and functional classification of the CARF domain superfamily, key sensors in prokaryotic antivirus defense, Punctuated equilibrium as the default mode of evolution of large populations on fitness landscapes dominated by saddle points in the weak-mutation limit, Unique genomic features of crAss-like phages, the dominant component of the human gut virome, Selection for Reducing Energy Cost of Protein Production Drives the GC Content and Amino Acid Composition Bias in Gene Transfer Agents, Can Environmental Manipulation Help Suppress Cancer?

Although less thoroughly characterized, several dedicated mechanisms of intervirus competition hav... CrAss-like phages are a recently described family-level group of viruses that includes the most abundant virus in the human gut.

A chat with Eugene V. Koonin To celebrate the 15th anniversary of Nature Reviews Microbiology and to give our readers a glimpse behind the curtains, we asked a few of our past authors about their views on microbiology, the journal and their experiences of working with the journal.

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